Is Maple Syrup A Colorectal Cancer Killer?
Can it be true? Can something as delicious as maple syrup really kill cancer cells? A recent study conducted by the journal Oncology Reports shows that maple syrup represses the growth and intrusion of colorectal cancer cells within the human body.
This new research referred to as “Inhibitory effect of maple syrup on the cell growth and invasion of human colorectal cancer cells,” examines the effects of three types of maple syrup, classified by color, on colorectal cell (CRC) proliferation, migration, and invasion.
Scientists' primary goal was to assess the suitability of maple syrup as a potential phytomedicine for cancer prevention and treatment.
From this, researchers found that "Administration of maple syrup inhibited AKT phosphorylation (a pro-cancer cellular signal transduction pathway), while there was no effect on ERK phosphorylation.” This conclusion suggests, "Maple syrup, particularly dark colored ones, might be suitable as phytomedicines, which have fewer adverse effects than traditional chemotherapy for CRC treatment.”
Current approaches to colorectal cancer therapy rely heavily on toxic drugs, such as fluoropyrimidines plus either oxaliplatin or irinotecan, which is considered the standard of care for advanced CRC. This approach can prove problematic because these agents can increase the chemo-resistant subpopulation of cancer cells, including the cancer stem cells, which are at the heart of cancer malignancy, as well as, having, a broad range side effects that are arguably a higher overall mortality risk than cancer itself.
Therefore, if proven to be successful continually, administration of maple syrup to treat colorectal cancer could prove to be an innovation of great strides — painless progress advancing us one step further to complete control over colorectal cancer treatment.